Your guide to a customized optimal nutrition
WHAT ARE MICRONUTRIENTS?
Micronutrients, as opposed to macronutrients (protein, carbohydrates and fat), are comprised of vitamins and minerals which are required in small quantities to ensure normal metabolism, growth and physical well‐being.
These are essential organic nutrients, most of which are not made in the body, or only in insufficient amounts, and usually, must be obtained through food. When dietary intake of a vitamin is inadequate, deficiency disorders result. Although vitamins are only present and required in minute quantities, compared to the macronutrients, they are just as vital to health and need to be considered in the context of nutrition quality.
These are inorganic nutrients that also play a key role in ensuring health, and well‐ being. They include the trace elements copper, iodine, iron, manganese, selenium, and zinc together with the macro elements calcium, magnesium, potassium, and sodium. As with vitamins, minerals are found in small quantities within the body and they are obtained from a wide variety of foods.
Micronutrients that are free floating in your blood and exist outside the cells, determined in plasma are called extracellular micronutrients. These extracellular micronutrients are a static measure of what is in your blood at any given time. These are dependent on your short-term intake of supplements or diet and give a direct assessment of your baseline micronutrient levels. Extracellular nutrient tests reflect a person’s diet over a relatively narrow time frame.
Intracellular micronutrients are the micronutrients absorbed by your circulating white blood cells and red blood cells. Cellular micronutrient absorption is an important step in maintaining and promoting optimal functioning of all our cells. It is important to understand that, even though you may be consuming an adequate or healthy diet or supplements, your cellular intake levels of those nutrients may not be sufficient and may still provide risks for deficiencies and the disorders associated with them.
ROLE OF MICRONUTRIENTS
Every physiological function in the body requires micronutrients to function optimally. Vitamins, minerals, and antioxidants play key roles in:
- Producing and releasing energy.
- Strengthening the immune system.
- Reducing systemic inflammation.
- Protecting against free radical damage.
- Maintaining a healthy hormonal balance (i.e. thyroid, sex hormones, adrenal hormones, neurotransmitters/brain hormones, etc.).
- Maintaining insulin sensitivity.
- Slowing down cellular aging.
- Promoting the health of all tissues: skin, bone, brain, breast, gut, prostate, heart, muscle, organs, etc.
- Protecting against the development, progression, and recurrence of cancer.
WHY TEST FOR MICRONUTRIENTS
Knowing both your extracellular and intracellular micronutrient levels are key to a thorough understanding of your nutritional requirements at a foundational level, which may contribute to your risk for disease, while simultaneously and positively impacting your overall health and well-being.
THE BENEFITS OF EXTRACELLULAR TESTING INCLUDE:
Identifying baseline nutritional deficiencies.
Detecting higher than normal levels of vitamins and minerals in your blood.
Identifying excesses of nutrients caused by uncontrolled supplementation, to prevent the increased risk of certain chronic diseases or nutrient toxicity side effects.
"Avoiding unnecessary spending on costly supplements.
"Providing a short-term nutritional status of the last few days.
Extracellular micronutrients have been well studied and deficiencies have correlated to multiple chronic diseases including cancer, Alzheimer’s, diabetes, and cardiovascular diseases. 1,2,3,4. Testing extracellular micronutrients also plays a role in patient management for such chronic diseases.
THE BENEFITS OF INTRACELLULAR TESTING INCLUDE:
Identifying functional deficiencies in intracellular micronutrient levels (cellular nutrient absorption deficiency.
Identifying essential micronutrient absorption deficiencies which cause or increase the risk of chronic diseases.
Providing a long-term nutritional status of the previous 4-6 months.
Intracellular micronutrients have been studied scientifically and have long been considered a more sensitive tissue measure of micronutrient absorption. For example, vitamin C levels in lymphocytes have been found to be deficient in Type 2 diabetes patients as compared to plasma levels. 5 RBC folate and magnesium are clinically more significant than whole blood measures of these nutrients. 6 RBC omega-3 and omega-6 fatty acid levels have been found to be markers of accelerated structural and cognitive aging.
VIBRANT’S MICRONUTRIENT TEST
The Vibrant’s Micronutrient test is the only test that provides a comprehensive extracellular and intracellular assessment of the levels of the most important vitamins, minerals, antioxidants, fatty acids, and amino acids.
Vitamin A Vitamin B1 Vitamin B2 Vitamin B3 Vitamin B5 Vitamin B6 Vitamin B12 Vitamin C Vitamin D3 Vitamin E Vitamin K1 Vitamin K2
Calcium Manganese Zinc Copper Chromium Iron
Asparagine Glutamine Serine
Coenzyme Q10 Cysteine Glutathione Selenium
Choline Inositol Carnitine MMA (Methyl Maloneic Acid)
RBC Folate RBC Magnesium RBC Omega Fatty Acids
HOW DO YOU ORDER VIBRANT’S MICRONUTRIENT TEST?
Vibrant’s micronutrient test is only available to order through your provider. If your physician is not in our network, please contact us.
WHO SHOULD RUN THE VIBRANT MICRONUTRIENT TEST?
This testing would be most beneficial if you:
Vibrant’s patented technology and reporting allows for high sensitivity quantitative detection of intracellular micronutrients.
Vibrant provides both extracellular and intracellular testing for a thorough understanding of your short-term and long-term nutritional status and requirements.
Vibrant utilizes highly accurate and highly precise testing, enabled by automation and advanced testing methodologies.
Clinically relevant RBC Folate, omega fatty acids, and magnesium are measured.
VWBC levels are normalized to total WBC count.
Fast TAT of 10 business days.
Vibrant provides comprehensive back-up testing to identify potential sources of malabsorption.
Vibrant’s clinical support team of highly qualiﬁed expert dietitians are available to provide support on dietary plans and supplementation for patients.
Vibrant’s micronutrient test uses advanced reporting with easy-to-interpret results and repletion suggestions.
1. Ames B. DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res. 2001;475:7–20. [PubMed] 2. Kamphuis, Patrick J.G.H., and Philip Scheltens. “Can Nutrient Prevent or Delay Onset of Alzheimer’s Disease?” Journal of Alzheimer’s Disease vol. 20 (2010): 765-75. doi:IOS Press Content Library. 3. Via, Michael. “The Malnutrition of Obesity: Micronutrient Deficiencies That Promote Diabetes.” ISRN Endocrinology 2012 (2012): 103472. PMC. Web. 18 Sept. 2017. 4. Klaus K.A. Witte, Andrew L. Clark, John G.F. Cleland, Chronic heart failure and micronutrients, In Journal of the American College of Cardiology, Volume 37, Issue 7, 2001, Pages 1765-1774, ISSN 0735-1097, https://doi.org/10.1016/S0735-1097(01)01227-X. 5. Yamada, Hiroshi, Kaoru Yamada, Masako Waki, and Keizo Umegaki. “Lymphocyte and Plasma Vitamin C Levels in Type 2 Diabetic Patients With and Without Diabetes Complications.” Diabetes Cares, vol. 27, no. 10, Oct. 2004, pp. 2491-92, care.diabetesjournals.org/content/diacare/27/10/2491.full.pdf. Accessed 18 Sept. 2017. 6. Cox I. M., Campbell M. J., Dowson D. (1991). Red blood cell magnesium and chronic fatigue syndrome. Lancet 337, 757–760. 10.1016/0140-6736(91)91371-Z [PubMed] 7. 8. Tan Z.S., Harris W.S., Beiser A.S., Au R., Himali J.J., Debette S., Pikula A., DeCarli C.S., Wolf P.A., Vasan R.S., et al. Red blood cell omega-3 fatty acid levels and markers of accelerated brain aging. Neurology. 2012;78:658–664. doi: 10.1212/WNL.0b013e318249f6a9. [PubMed] 8. Achieving Iron Balance with Diet, Iron Disorders Institute, 18 Sept. 2017, www.irondisorders.org/diet/. Accessed 18 Sept. 2017. 9. Pelton, Ross, James B. LaValle, Ernest B. Hawkins, and Daniel L. Krinsky. Drug-Induced Nutrient Depletion Handbook. 2nd ed., Lexi Comp, 2001.